DPCstruct | MC2776

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)130 ± 11 aa
Standard deviation of domain lengths10.79
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.10
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)52.06
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377XQJ9 2-121 EKHLLISKGCKGWGGPLTITLGQGKKIAYITGGIRPPVVDRLSELTGWPSIDVFKNGEPPAEEIGLMVIDCGGTLRCGLYPKRGIPT…
A0A1M6H257 3-124 NYRSIVVKSSNGGFGGPLTITPTEKQHKIMYLIAGGDRPEVVDKICELTGMEAVNGFRYRVQEEEMAVAVIDCGGSLRSGVYPRKGI…
R2XH40 2-122 None
E2SMN4 28-173 None
A0A2X1QSL1 188-311 None
A0A7C5E396 35-159 None
A0A377YFP6 2-123 None
A0A2X3F262 271-393 None
A0A5D4NC88 160-284 None
A0A7V8IJB7 1-127 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.