DPCstruct | MC27725

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)112 ± 25 aa
Standard deviation of domain lengths24.75
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.46
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)28.38
Pfam Score97.73
Assigned Pfam label(s) PF00696- PF09269

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0P0XA81 34-115 NEFEIFHDKGTNTWNVVGAGIERFVQMTNWQYSESLKRFQHALEACGVNKTLIKRGVKEGDTVVVGEMEMVWTDEPSKTRSS
A0A7K1BMZ3 18-112 EEVRGARSVEPELDGFVVHRPIPEGIRIEREDDGSYRVVGRAAERAVALSDLTNLEALDFAHSRLKKIGVDKALARAGATEGDTVRI…
A0A2G6EZA6 5-76 None
X8A587 21-120 None
A0A2H6K9W1 685-803 None
A0A6G3V1B5 1-80 None
A0A7S2XZJ3 36-128 None
A0A061D5S3 441-559 None
A0A3S3Q0V8 465-607 None
Q4N915 261-382 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.