DPCstruct | MC2749

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)140 ± 19 aa
Standard deviation of domain lengths18.79
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score76.70
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)30.47
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A512E4R2 40-168 SLSRSIDANARAAQIEIFGGEVIVPATEQNRGTASAPTRGGTVVRAFWWGFHIQISHEDVQGVVSAIDGAKSLISAISPAAPAKVRP…
A0A409W5B4 514-640 VPSDTKLSVQAMWWGYRLYLPPPVLEILDDKTLEATKRAAMITTALTWFFNNLPINSLPVAVRPALLLLQRIAPFVGYIGTFISWSW…
A0A543GCU9 5-116 None
A0A1J8Q690 21-167 None
A0A4S8MQI0 167-308 None
A0A4P9Y7G1 50-168 None
A0A146I9T3 535-681 None
V2XDV8 314-464 None
A0A1Y2GQT3 258-412 None
X8JKL7 105-254 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.