DPCstruct | MC274

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)224 ± 18 aa
Standard deviation of domain lengths18.43
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score94.00
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)33.26
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y5J2U7 24-274 EGWGVIVDQWGGYDVSGMSGSTIHNGGYGFCMNTFDLAWPLTAMLRYDQRYARAVGRWALNAANTARLFYPNDIPDGLQALPNRKAL…
A0A645GZD5 1-220 MNSMKMAWPLVPMVKYEPRLARAIGKWMLNNINASRLFFPNEIDDKHQWLPEMKDYTKSIVAYEGLRFEDCYNKPELKGVHPVALGD…
A0A097EP47 367-611 None
A0A3M2HZ19 151-392 None
A0A660XN17 1-214 None
A6DPF0 685-924 None
E7G6G2 80-320 None
A0A7K0HEV2 33-257 None
A0A1I0V8X6 333-543 None
A0A7W0XGM8 210-418 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.