DPCstruct | MC27365

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)204 ± 14 aa
Standard deviation of domain lengths13.61
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score83.94
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)23.79
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X4YHW2 13-202 NKDFKIDWEYTISFDGFKKYIDENGIKKYQLILDKEGNKNEDSKTLVAARKMNIKNVIEDDSQNHIGIQIADMLAGIISKFIKMLEE…
A0A414XGU9 1-223 MIDESFVSFNTKNYYSWDYELETDLILNKIENDTRNNYSFIFDEGTKASKILKSKLDKQNVQVIESDSKKDTMIRFVDWMATFFGKL…
R8DMD4 122-332 None
A0A806T6Z1 49-241 None
A0A2Z4VW94 80-287 None
A0A645DQL5 102-300 None
I0SMX3 439-649 None
A0A7C7AF13 71-249 None
A0A1N6GN34 1-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.