DPCstruct | MC27300

Metacluster Properties and Pfam Annotations

Number of structural domains157
Mean domain length (aa)397 ± 76 aa
Standard deviation of domain lengths76.38
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score89.68
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)17.12
Pfam Score93.94
Assigned Pfam label(s) CL0714- CL0026

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C2C4J1 9-372 GWTFYYPFSAQSGSGVDFYMAAILLLGFSSLLGNANFIATIYNLRAQGMSLWKMPMYVWSVFAASLLNLFSLAGLTSASLLILLDRK…
A0A1G3BIF4 59-520 TARNFIFSSVVWLGLVVSVALVLALKFVWPDFLGGVAWLSFGRLRPFHVNGALFGWLSMSSLGIMFYILPKLTGARLWSERLGNVTC…
A0A538IXA6 100-582 None
A0A7C4GAJ0 34-501 None
A0A800CGA1 2-290 None
A0A349WG64 2-253 None
A0A7C5Y474 3-330 None
A0A2V8YVS7 2-299 None
A0A7S0A5K4 106-641 None
A0A350XPJ3 19-469 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.