DPCstruct | MC27279

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)118 ± 13 aa
Standard deviation of domain lengths13.27
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score86.21
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)29.31
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G5K3D4 4-85 TINIEARKPVWIALSEFYLDTELQGMDFRHIARIIMESPYSIEEVKEINKYEIFPVLQKNLTSVAGEWAGFQEECLVENILR
Q21PR8 1-128 MLSNEEIDKRFPVWKAMSDLFLDTDLQESDYKFIANTVLKSGYSPREINSILWQEVLLGVGDNLRCIAGEWAGFNPVWLKHRMLDVL…
A0A5M3MEX2 9-128 None
A0A560J923 34-166 None
A0A553UR31 3-133 None
A0A7H8PS88 14-134 None
A0A7X1NU32 12-136 None
A0A4Y7QBB5 3-118 None
A0A6A5TH31 2-138 None
A0A2N3T8T5 136-255 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.