DPCstruct | MC27233

Metacluster Properties and Pfam Annotations

Number of structural domains86
Mean domain length (aa)117 ± 24 aa
Standard deviation of domain lengths24.39
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.46
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)42.09
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4C1W061 92-208 MKQFVKALRQDSEAFQYLKSFFPKLSEAKIKAGIFIGPQIKKIMASEQFLRLLSTHEKQAWLSLKAVIHGFLGNRKAENYTELITDM…
A0A4Y2DTE0 16-141 KIFVKALDREGVAFLHLGNKFKHLSDAKVKEGMLIGPQIKAVFRDEEFEKKLSGAEKAAWLAFKSVCTHFLGNKKAENYEDLVGDMV…
A0A6P4LE67 65-147 None
A0A4Y2T2M3 90-211 None
A0A4Y2A6Y3 145-283 None
A0A4C1UC60 19-135 None
A0A4Y2CZS0 1-90 None
A0A4Y2CSS9 178-292 None
A0A4Y2UEI9 31-157 None
A0A7T8QVG0 113-232 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.