DPCstruct | MC27227

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)78 ± 13 aa
Standard deviation of domain lengths12.60
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score71.77
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)77.54
Pfam Score100.00
Assigned Pfam label(s) CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2DI13 1-87 MRSAASIGQQVSDKAVGLVPAAKMAGYQDLSNFERGLIVGAREMRHSISEVAMKFGYSHTTISRVYHEYRVSGKTSKLEHRRDQKRP
A0A4Y2EGY1 1-62 MAGYQDLSKFERGVIVGAREMGHSISEVAIKFGFSRTAISRMYREYRESGRTSNLRHRCGRK
A0A4Y2BBL1 1-81 None
A0A4Y2VQX6 1-100 None
A0A4Y2VAI9 89-177 None
A0A4Y2CZN9 1-63 None
A0A4Y2B0P5 139-207 None
A0A4Y2DRJ3 4-66 None
A0A4Y2FPI0 63-145 None
A0A4Y2GUL8 9-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.