DPCstruct | MC27143

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)236 ± 62 aa
Standard deviation of domain lengths61.71
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score87.21
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)30.03
Pfam Score97.62
Assigned Pfam label(s) CL0062- PF04749

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I0T9L6 15-145 AGIMVPSLIFIITVTVVSSFFPTQTGAILNVVKNWIFVNLNWIYVWSVTIFVIFLLVLTFSKYGAIRLGDDDEKPEHSFFSWISMLF…
L1JML1 10-243 AFRLPPLDLALNPVVAFFAFGIIWAFIVACIAVPVEFSGQIWWWKRQILSTFLWLYYLCENVWVIFIIWLCYSRWGTFTLGESQRDT…
A0A0Q8NI21 10-192 None
A0A411YB42 28-168 None
A0A2M9AJI4 2-295 None
A0A1A0J9S5 2-218 None
A0A7M5UUX0 61-359 None
A0A4R6DWJ2 2-261 None
A0A6N3UDA7 43-219 None
A0A6B8TM20 4-257 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.