DPCstruct | MC27141

Metacluster Properties and Pfam Annotations

Number of structural domains124
Mean domain length (aa)290 ± 53 aa
Standard deviation of domain lengths53.30
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.18
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)20.44
Pfam Score98.93
Assigned Pfam label(s) CL0306- PF19324

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A653DE58 40-345 IYKTEAKKIRVYAVNRYWEYLKNYDKVLEKRFPEAMKVYRVFVDGVKEFMKDTKEYFRVVVILNKSNFDFSKLLRREIELYHQMPKD…
L1JBY8 6-298 DEPKPSWLATKWAHVKHEAYHYWLGTKLLGKEIGICVGILKQILRGEELSRREYRQLRTTSTDLLKMVPFAIIVLVPFMELALPVIL…
A0A7R9YFW8 26-365 None
A0A179I784 52-250 None
F4PJ15 100-453 None
A0A821EPR6 2-201 None
A0A1Y2HEA9 13-260 None
A0A2S4KML7 347-652 None
A0A2H3CAH1 29-305 None
A0A0M3IPB5 2-172 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.