DPCstruct | MC27123

Metacluster Properties and Pfam Annotations

Number of structural domains77
Mean domain length (aa)118 ± 21 aa
Standard deviation of domain lengths20.62
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.87
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.55
Pfam Score88.60
Assigned Pfam label(s) CL0010- PF04981

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2CC88 164-279 AHKKTFYYLEQLILKHKLHSNALNIKEIHDGIDFYYGLKQHAQKMVDFLQCTVPCRSKTSQRLISHDIHSNTYNYKSTFSVEIVPVC…
A0A1J5T6R0 64-173 QVCENCSRQAGGYFESTLQLRSKRKSVLASAIEKVRNEISSAPPEIFSTMDAPVRGGHDFQLSSTDKARTIARLMINSYGGSIKEAR…
C3ZPJ6 66-166 None
A0A816RAV9 502-649 None
A0A2G3B957 107-221 None
A0A803Q3I8 2-103 None
A0A2I1DUE2 149-294 None
A0A6B2CD18 76-170 None
A0A2R4ZMR4 79-217 None
A0A7C1BHM2 108-207 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.