DPCstruct | MC2712

Metacluster Properties and Pfam Annotations

Number of structural domains500
Mean domain length (aa)101 ± 16 aa
Standard deviation of domain lengths15.87
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.02
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)35.78
Pfam Score98.90
Assigned Pfam label(s) PF03381- PF02161- PF02159- PF00104- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182WW99 672-774 None
A0A7R9LKX7 472-556 None
A0A2A2JIH5 83-205 None
A0A2A2J9G1 1-98 None
E4WTY2 270-362 None
E3NNG1 19-120 None
A0A2G8K829 103-196 None
A0A1I8BDZ3 305-392 None
A0A1I8B6U2 14-134 None
A0A1I8B188 73-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.