DPCstruct | MC2712

Metacluster Properties and Pfam Annotations

Number of structural domains500
Mean domain length (aa)101 ± 16 aa
Standard deviation of domain lengths15.87
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.02
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)35.78
Pfam Score98.90
Assigned Pfam label(s) PF03381- PF02161- PF02159- PF00104- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I8EGX4 28-104 SGKSKDLCVVCGDIASGNHYKVLTCEGCKSFFRRSIQKKAKYHCVRSGNCPITAKDRNKCQKCRLDKCLQMGMDVNS
A0A3Q2EHE3 6-104 KAQTKLSVMDVEELCPVCGDKVSGYHYGVLTCESCKGFFKRTVQNKKAYVCVGKQQCQIDQSQRKRCPFCRFQKCLNAGMRLEGKLD…
A0A7R9KDQ1 141-248 None
A0A7R9KEI7 235-320 None
A0A7R9KHR3 160-261 None
A0A7R9KKQ9 3-94 None
A0A7R9KKT7 4-101 None
A0A7R9KT34 64-182 None
A0A7R9KN42 17-87 None
A0A7R9KQR0 2-93 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.