DPCstruct | MC27023

Metacluster Properties and Pfam Annotations

Number of structural domains111
Mean domain length (aa)191 ± 34 aa
Standard deviation of domain lengths34.24
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.05
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.27
Pfam Score100.00
Assigned Pfam label(s) CL0198

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E4RPA3 9-172 YEKYLKEYDNTSGLYPGALAELGEKYHQKSYLSREELYELAHLNSTRSSYHVKKNPEDRVEKLTGIAYQIDDTFARLALYSSLMGIG…
A0A199UGG0 16-215 GAYAARVETLAGAAASKRELLPLDSFYRGDLPLLLRRRGPKPFLSKSELLRVVQWKLSRGQWRPRLMGYAEALGEAEVEAASRAALA…
A0A7R9PNJ1 65-236 None
R1EA12 12-150 None
A0A1J5A9H9 8-185 None
Q2HDK7 18-225 None
A0A830CEY0 1-170 None
A0A4S0N9S7 75-315 None
K1Q8C3 2-156 None
A0A1Q5AQF2 12-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.