DPCstruct | MC2698

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)226 ± 19 aa
Standard deviation of domain lengths18.60
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score70.05
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)27.83
Pfam Score83.33
Assigned Pfam label(s) CL0247- PF04457

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S8WGV6 1-238 MALKLVRSLLSNSRLHKDRFIVVYRDNFAGLLEEPLNAFSWNFDGDFGWCPIVVPGWQIEKLKYNSRVVWSKTLERQFDEVYRLCLE…
A0A2R5GI69 1-230 MRPAMDVVNRILWDEGLPNHAFVVGYLDRFVGVKEKAISAFNFHDDFGSISHTETAIPQTRIQYLKYVHQDGSRLVWDRRPESRADD…
U9SIQ6 6-195 None
A0A654H4G8 4-236 None
A0A074ZFU0 162-402 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.