DPCstruct | MC2697

Metacluster Properties and Pfam Annotations

Number of structural domains682
Mean domain length (aa)146 ± 24 aa
Standard deviation of domain lengths23.85
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)10.42
Pfam Score22.27
Assigned Pfam label(s) PF20458- PF18906- CL0187- PF06995- PF05638

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A844LQX2 2-135 None
A0A1C6ARV6 145-286 None
A0A2E2ZRM4 6-129 None
A0A1A9WVW9 4-125 None
A0A0Q6WN21 7-154 None
F6DTF5 8-143 None
A0A7J0A6Q5 37-189 None
A0A7C3C017 84-242 None
A0A379MRK3 14-187 None
H8NWZ8 6-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.