DPCstruct | MC2697

Metacluster Properties and Pfam Annotations

Number of structural domains682
Mean domain length (aa)146 ± 24 aa
Standard deviation of domain lengths23.85
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)10.42
Pfam Score22.27
Assigned Pfam label(s) PF20458- PF18906- CL0187- PF06995- PF05638

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W4YVZ7 13-169 None
A0A2D4R0P8 32-239 None
A0A1H7Z068 6-155 None
A0A447Y276 453-608 None
A0A257QTN4 3-149 None
A0A355JCM5 1-137 None
A0A2E8BSS3 36-156 None
E2CKR5 4-112 None
A0A6V8M2H3 1-102 None
A0A4R6GVF8 8-134 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.