DPCstruct | MC2697

Metacluster Properties and Pfam Annotations

Number of structural domains682
Mean domain length (aa)146 ± 24 aa
Standard deviation of domain lengths23.85
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)10.42
Pfam Score22.27
Assigned Pfam label(s) PF20458- PF18906- CL0187- PF06995- PF05638

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A524IJW0 43-207 None
A0A2K3YPY8 13-192 None
A0A431JZK7 9-136 None
A0A1Z4H1N2 11-161 None
A0A5E4LK79 10-173 None
A0A5E4LVE9 2-281 None
A5ZE27 1-143 None
U2M6B1 185-337 None
A0A377K283 1-163 None
A0A1V2H6I8 37-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.