DPCstruct | MC2697

Metacluster Properties and Pfam Annotations

Number of structural domains682
Mean domain length (aa)146 ± 24 aa
Standard deviation of domain lengths23.85
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)10.42
Pfam Score22.27
Assigned Pfam label(s) PF20458- PF18906- CL0187- PF06995- PF05638

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5D3FRA8 9-146 AAAHNFGLQIDGTTVEYLQRVSGLGQEQDVIEFKQNSAKGQPATAKMPGVAKAGEIQVVRATTQSQAFSDWIKKSFEGDMSAARKNA…
A0A285QMK2 12-150 HIQFGEQLLLGPGTAYRWRSLTGWEDSPPLDSGTVNRPAGHGAYPGELWAQPRTITVEGITIRAPVSQLGETVRRFGAGTSSMDAEQ…
A0A2D6E6J6 20-217 None
A0A0M9ZZF0 4-167 None
A0A2T2RS55 128-239 None
A0A377ZDF1 10-151 None
A0A7X7VGY4 2-147 None
A0A2D6E271 52-178 None
A0A2D6E635 19-200 None
A0A243RVS7 122-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.