DPCstruct | MC26963

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)130 ± 13 aa
Standard deviation of domain lengths13.23
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score91.16
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)44.03
Pfam Score100.00
Assigned Pfam label(s) PF09615

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645FZ90 1-129 MLLQVTAFVRIGAGQEVFPSQELILDRGRGDKSKTLYHVSNIAGIHSQKIGNALRTIDTWYEGADEMGPIAVEPYGSVTTQGKAYRQ…
A0A135I3D1 19-159 WLADIKANVSASFMQEIFPSQLFSDAKDGSNLGREYAKVRSGDGQIWPSLNAEKIGAAIQLIDDWWADEADKRLRVHEYGGDKKYHI…
N8PWM2 86-234 None
A0A5C4Q025 2-107 None
U7UQX7 196-313 None
A0A6N8EJ92 154-272 None
A0A4S8F9N2 35-164 None
A0A3S4E3Y5 32-180 None
A0A401X792 235-356 None
A6FFZ7 160-291 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.