DPCstruct | MC26912

Metacluster Properties and Pfam Annotations

Number of structural domains138
Mean domain length (aa)173 ± 26 aa
Standard deviation of domain lengths26.45
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score86.27
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.75
Pfam Score87.24
Assigned Pfam label(s) CL0244- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8CEF5 6-151 DHGGVTNFGITAVAWGQYKKLNRPCTAAEMQAIARADAVEFYRQKYIVNSAFKAVAYEPLRAQLIDFAVNSGETRATRWLQRAIGLP…
A0A825BCJ3 12-136 NADIRSASEVLYTNITLKKMVFDFYEREFWNKMRLNAIESQIIADELFCFGVNAGIKTAVKLAQKLVGTPLDGIMGVQTLRALNSAD…
A0A7X3UHW1 8-212 None
A0A1F3EM28 4-137 None
A0A3D5BUW8 63-278 None
A0A1I5TV14 10-135 None
A0A3P1W5B0 199-375 None
A0A0X8JI06 20-227 None
A0A258GU21 349-530 None
A0A2A7U161 91-268 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.