DPCstruct | MC26862

Metacluster Properties and Pfam Annotations

Number of structural domains1129
Mean domain length (aa)190 ± 40 aa
Standard deviation of domain lengths40.07
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score84.69
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)14.15
Pfam Score90.30
Assigned Pfam label(s) CL0223- CL0023- CL0126- CL0020- CL0466

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6G7Z7X5 32-215 AADGPLASVSLWQGDLTALRVDAVVNAANSAMLGCFTPGHACVDNAIHTAAGPGLRAECADLVGAQGHPEPTGSAQVTGAYHLPARH…
A0A1U7SDX6 50-159 EKVSLYRGDITLLEVDAIVNAANSSLLGGGGVDGCIHRAAGPCLVAECRNLSGCETGQAKITCGYDLPAKYVIHTVGPIARGHITDI…
A0A355U0A9 3-181 None
A0A355RNB9 6-168 None
A0A7C5NG33 5-192 None
A0A2E4QX53 190-417 None
A0A4Y7JTB8 13-191 None
H0SW98 4-148 None
A9JRH9 96-288 None
A0A7Y1ZT93 391-576 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.