DPCstruct | MC2686

Metacluster Properties and Pfam Annotations

Number of structural domains5010
Mean domain length (aa)306 ± 70 aa
Standard deviation of domain lengths70.07
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.84
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.64
Pfam Score74.00
Assigned Pfam label(s) PF02729- CL0022- CL0113- CL0110- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A383VB26 352-555 None
A0A3L6SJF5 56-453 None
A0A378JFA1 139-410 None
A0A7S4L8X4 23-354 None
A0A813HNF0 625-973 None
A0A445F1J7 160-473 None
A0A447RZJ2 179-443 None
A0A0F9KV51 1-269 None
A0A813GM29 33-398 None
A0A813GBF9 22-295 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.