DPCstruct | MC2686

Metacluster Properties and Pfam Annotations

Number of structural domains5010
Mean domain length (aa)306 ± 70 aa
Standard deviation of domain lengths70.07
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.84
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.64
Pfam Score74.00
Assigned Pfam label(s) PF02729- CL0022- CL0113- CL0110- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I6S566 22-258 None
A0A6M5XUC2 4-164 None
A0A0B7I8Y6 2-194 None
A0A3R7Y9X5 42-256 None
A0A3E0NYY6 473-857 None
A0A438F2I2 77-497 None
A0A1W9U2K1 4-300 None
A0A353V1K7 104-428 None
A0A3D9LAN8 150-531 None
A0A3D9L8T0 270-594 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.