DPCstruct | MC2686

Metacluster Properties and Pfam Annotations

Number of structural domains5010
Mean domain length (aa)306 ± 70 aa
Standard deviation of domain lengths70.07
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.84
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.64
Pfam Score74.00
Assigned Pfam label(s) PF02729- CL0022- CL0113- CL0110- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A447TGX7 10-264 None
A0A2N0VGH2 129-469 None
A0A2G6QMB3 349-663 None
A0A7S1Y7R0 14-295 None
A0A7G9NZ99 21-273 None
A0A7Y9VMH2 59-352 None
A0A4T2C3U5 172-550 None
A0A4T2BX30 10-327 None
A0A6B2LHY0 23-213 None
A0A2V8HMX5 141-517 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.