DPCstruct | MC2686

Metacluster Properties and Pfam Annotations

Number of structural domains5010
Mean domain length (aa)306 ± 70 aa
Standard deviation of domain lengths70.07
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.84
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.64
Pfam Score74.00
Assigned Pfam label(s) PF02729- CL0022- CL0113- CL0110- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T1JEU6 2-172 None
A0A3M0YUP2 3-231 None
A0A378I2E9 45-348 None
A0A183SXD2 5-253 None
A0A239Q2Q9 485-790 None
A0A0D6PL52 4-192 None
R7JPD8 2-160 None
A0A4S8IVZ1 180-615 None
A0A7Z0ZXI8 7-371 None
A0A7X9T473 7-334 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.