DPCstruct | MC2686

Metacluster Properties and Pfam Annotations

Number of structural domains5010
Mean domain length (aa)306 ± 70 aa
Standard deviation of domain lengths70.07
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.84
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.64
Pfam Score74.00
Assigned Pfam label(s) PF02729- CL0022- CL0113- CL0110- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J2R1M7 70-298 PVFSFSKTADYQDIMYPAWTFWEGGPAVWPIYPTGLGRWDLMMDDLKKSAAQWPWKNKESKGFFRGSRTSPERDPLILLSREAPELV…
A0A1H0AH69 17-317 KITAERIKQGIENRSHKVSVISSTEEGAPIPENIDLVHGFHAYKFAIFQKKYNIHLPYILTLTGTDINQNLEEEDKRDVILQCLQNA…
A0A7R7GC75 27-319 None
A0A7S1XWM6 257-466 None
A0A419DWA1 328-668 None
A0A3B9ZIS5 344-643 None
A0A7W0Q936 43-298 None
A0A418WTC5 16-346 None
K8F6C7 744-1131 None
A0A7R9Q310 39-412 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.