DPCstruct | MC26858

Metacluster Properties and Pfam Annotations

Number of structural domains153
Mean domain length (aa)145 ± 30 aa
Standard deviation of domain lengths29.61
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.97
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)24.99
Pfam Score98.53
Assigned Pfam label(s) CL0105- PF01252

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I4EDZ6 2-87 None
A0A2D5K544 8-149 None
A0A847EUX9 2-145 None
E4MA23 61-263 None
A0A6N6SMQ4 16-199 None
A0A354Z5G3 16-166 None
A0A101W0A1 9-155 None
A0A1X1TKA5 33-182 None
A0A499UV00 2-90 None
A0A8A7W6C7 12-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.