DPCstruct | MC26849

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)255 ± 21 aa
Standard deviation of domain lengths20.71
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score85.52
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)24.48
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R6NY95 1-276 MRTKGNESVYSEFEKLMQENRCQQAAELLREKKGISALLRNMDYIISRMDREDEQTFLSEFPEDCSTLILLQLLFRYEGVQRKDGRI…
A0A7T4U0C4 187-463 TWQSRVEDALGRWDTTAAARLLGERPGELLRRLDLLLARSGSATLPEPVAEALARALPHTASGPLLGAYGQLMIRTAPGRRRVFFPR…
A0A1H1GUN9 74-340 None
A0A1Q3N3R6 353-587 None
A0A7Z0TH74 1-222 None
A0A563VYI6 38-297 None
H8H253 442-721 None
A0A6S6UMK4 1-238 None
A0A7S2D9B4 127-371 None
A0A7X8X1K2 316-578 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.