DPCstruct | MC2681

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)157 ± 2 aa
Standard deviation of domain lengths2.21
Length coefficient of variation0.01
Mean AlphaFold2 pLDDT confidence score77.63
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)44.21
Pfam Score100.00
Assigned Pfam label(s) PF10271

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B4WDX7 1-160 MPTHTCPPHTHSHTPELIRAEVEELKSDFNRRIKEVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLMSQLLP…
A0A0V0V7W5 489-641 LIHACSVVPSQIREEVDVFISDVYNRLKQCLFAAFTTAYYAVFIPCGFAPAYLYIDYVWVAEMSFIVFLTSGTLYLTYLFPIQLCDQ…
A0A139WAV5 518-675 None
A0A2I2YTX8 1-157 None
A0A6J2DEP1 222-378 None
A0A6G0TNP9 1-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.