DPCstruct | MC26738

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)307 ± 66 aa
Standard deviation of domain lengths66.33
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score74.81
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)33.55
Pfam Score89.70
Assigned Pfam label(s) PF19257- PF14443- CL0306- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183L2S7 62-383 TKPASRERDVHPSSSDQRRVDKKRSHVLNRDDHSIKKSPNRDRRRTPVDSVSTRHSSPTTDLYCRTPINPKRMLNVKEYLFSDLQRR…
A0A7J7TRW7 20-256 SPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMED…
A0A1I8GUZ2 42-398 None
A0A6N2NDZ0 16-258 None
A0A6P6KVF6 30-293 None
A0A183VJ51 34-363 None
A0A564Y663 60-401 None
A0A1D6LSU2 481-728 None
A0A5K3F5F6 60-393 None
L1IE93 1-300 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.