DPCstruct | MC26687

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)157 ± 18 aa
Standard deviation of domain lengths17.81
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score86.87
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)40.96
Pfam Score100.00
Assigned Pfam label(s) CL0254

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U9HL98 21-180 ADWTDDQIWALNRGGHDPKKVYAALKKAQETKGKATVILAHTVKGYGMGDTAEGKNIAHQVKKMNMDGVRYIRDRFNVPVTDEQVEN…
A0A447QCH5 349-515 VKDMTDDEIWALNRGGHDPKKVFAALKKAQDTQGKPTVILAHTIKGYGMGETAEGKNIAHQVKKMNMEGVHHFRDRFNVPVADAGIE…
A0A6F8XYW0 206-340 None
A0A6H2FPK2 350-535 None
A0A5E6NIZ4 1-165 None
A0A090P419 172-326 None
X8FGN8 29-178 None
A0A024HQC2 167-343 None
A0A7R9AF54 1-138 None
A0A4D4MN44 156-296 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.