DPCstruct | MC26598

Metacluster Properties and Pfam Annotations

Number of structural domains319
Mean domain length (aa)91 ± 10 aa
Standard deviation of domain lengths10.25
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score84.99
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)20.35
Pfam Score92.66
Assigned Pfam label(s) CL0077- CL0437- CL0329- PF21018

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3R6RPA7 5-96 SMLLESFYAFHLTISDKMVGRAMTDLERRFAVFEGPVLEDGQAILTGRAPVSSLDGYQTEVTVYTSGLGQLVCTLDGYGPCHNEEEV…
A0A6C0PZ14 22-113 RAGTVVCEPMNHFRLDVPADTFGAVLPALARLRAVLHTPSARGASYVVEGEIPAAEVHALEQLLPTLTSGEGVLEAAFDHHRPVRGT…
A0A7R9KJ60 649-734 None
A0A1R3KGV7 462-548 None
A0A7S0LZK5 3-86 None
R5VIX1 6-94 None
A0A2R6KT10 1-68 None
A0A2K5N9N7 338-426 None
A0A7S4NVT0 223-305 None
A0A1I8IMR4 150-234 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.