DPCstruct | MC26581

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)227 ± 41 aa
Standard deviation of domain lengths41.11
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.33
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)26.68
Pfam Score100.00
Assigned Pfam label(s) PF12246

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067N5K8 10-221 HTAIKASRVNDKFQDPLYLFLELVRAGVMHGNLWSARPHSGGPSFGTDEEKKCMLLIMRVMSIVPLNSKQQPWSGPLSRELLVFNSF…
A0A2G4SP67 179-401 VHTPWGKALHVSLKGDDVSRPMQEALLTALELIRFEVLTNKTFSKTYTRPLGNELEQKNIILLSRALSLLPIKLKNMQWLGPLNRDL…
A0A317XBK0 1-136 None
H8X6Z5 502-796 None
A0A0F8X2J2 498-722 None
A0A7J6QGL2 179-454 None
U9TB33 35-270 None
A0A512U627 533-825 None
A0A4Q1B8A0 292-528 None
A0A6A5SDZ8 1-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.