DPCstruct | MC2653

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)98 ± 12 aa
Standard deviation of domain lengths11.62
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score81.34
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)28.32
Pfam Score92.75
Assigned Pfam label(s) PF10785- PF12853

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K1KHI8 84-177 AMGIFLDEPKFPVIERNPTASSTISNFSFSDYVRIAAFTGGSLPVGYLAGGSVNIRGPSMYTAGIIGLMGGFMYAYQCSAGRLMGMF…
A0A1B9GXT8 3-103 LKQTVQPYPLIDADPHFSRVVRYMRPSDYVTWAGATAAGPGLLWAFEKADPTRSTKASLRSALRLTGWLGFCAGFMLAYQRSTARFW…
R9P0Y7 54-155 None
K8EA67 89-186 None
A0A2P4YKI8 2-97 None
C1MIP4 16-98 None
A0A2P5EXJ3 48-131 None
A0A7S2T8V2 67-152 None
A0A1R2CR92 24-141 None
A0A448ZTB7 15-103 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.