DPCstruct | MC26518

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)178 ± 11 aa
Standard deviation of domain lengths10.87
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score81.75
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)44.74
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1D6M1A4 128-308 SLPPSAAEVQRTECLRSLREVATSLSERPARGDLTGEVCHWADGYHLNVALYEKMLGSVFDILDEGKLTEEAEEILELLRSTWRTLG…
A0A438I8N7 1-199 MLTSHAFSLPPSTGGLQRTECLRSLREIAIPLAERPARGDLTGEVCHWADGYHLNVRLYEKLLLSVFDILDEGKLTEEVEEILELLK…
A0A2T7CYW2 324-504 None
A0A287HTC5 128-308 None
A0A0A9DUI8 35-210 None
U5DD15 330-504 None
A0A0P0WDQ1 1-202 None
A0A0D2TDU3 5-178 None
A0A438C2C3 2-156 None
A0A446SHG5 6-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.