DPCstruct | MC26493

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)143 ± 19 aa
Standard deviation of domain lengths18.54
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score88.76
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)29.39
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A423SUH8 12-138 VSYFAAGIVAHLVCAGHDSWDESGISKEDLLEELGKVVTSWEQPKDEMVAYRSFQPFIPLLTALNMHQVQLWAVWALHHVTTKNSKR…
A0A2U3Z1Q1 28-167 SNLLESKADGIEVSYNACGVLSHIMFDGPEAWGICEPQREEVEERMWAAIQSWDINSRRNINYRSFEPILRLLPQGISPVSQHWATW…
L9KLK1 669-820 None
A0A4Z2DI96 223-389 None
A0A654HIU9 204-357 None
A0A672Q920 406-547 None
T1GPQ1 32-158 None
A0A2H2JHR5 23-163 None
A0A6G3MGR4 148-299 None
A0A7I8VJA4 328-465 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.