DPCstruct | MC2648

Metacluster Properties and Pfam Annotations

Number of structural domains141
Mean domain length (aa)186 ± 40 aa
Standard deviation of domain lengths40.27
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.07
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)22.63
Pfam Score87.75
Assigned Pfam label(s) CL0425- CL0266- PF19530- PF00662

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A520K562 8-171 KSLLMGYIFALAGGAAILYAISTVKEAGQYVCALLYMGSALGAIFAGDFFTLYIFWEIMAFSSLGLIWYEGSRRARDAGMRYILFHL…
A0A2G3DGW4 26-175 YIECTEMAITEFLLFVLAATLGGIFLCGANNLIRMFQAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGS…
A0A4T0E3H3 67-249 None
A0A535AI42 1-205 None
A0A2H9T822 7-228 None
A0A7C7HXR3 2-118 None
Q9TD60 1-144 None
A0A381GJB3 11-198 None
A0A832C8P6 49-297 None
V9P4U4 62-256 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.