DPCstruct | MC26457

Metacluster Properties and Pfam Annotations

Number of structural domains1390
Mean domain length (aa)388 ± 97 aa
Standard deviation of domain lengths97.17
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score82.63
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)16.36
Pfam Score84.59
Assigned Pfam label(s) PF03381- CL0486- PF03621- CL0219- CL0314

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U9H8B8 76-426 NLAANCLDRHLATRGDQTAIIWEGDDPDQSKHVTYKQLHHDVCQFANVLKGLGVKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVI…
A0A6N7FGK9 42-456 AAALAAAGVRLGDRVAIDLADPLETVIAFLGGLKAGAVVAPLNPRLTPEERDRLVADLAPAHVMREIPTGEADYPAAALDGAAPAIV…
A0A814VL66 431-841 None
A0A1I8IVH7 308-935 None
A0A1I8IM89 14-317 None
A0A0K0E2M9 319-731 None
A0A6I6Q6P8 294-590 None
A0A7K0FHZ0 5-341 None
A0A1Q9TE80 24-395 None
A0A4Q6GDZ6 395-813 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.