DPCstruct | MC2644

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)165 ± 8 aa
Standard deviation of domain lengths8.20
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score91.89
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)33.31
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V8GCX0 2-153 NGIMAFQNAGGRHLALGANGFYWRCAFHPKAPAAVEVRRGMAGTRTWESQPGEVHLAGTGEPGALWRHSGFAPQKLIGVGFSAMVYD…
A0A4R4RV86 1-156 MAASYLGGNGFYWFVGLDPEEGHTIEVRRCGASTRAWESEPGEWHLSTTGDLGGLWRMRGRPPQALLGVGFTAQGQGPGRPYARQPD…
A0A2E9RVV8 738-902 None
A0A1M3AJ30 263-430 None
A0A263DHB0 510-682 None
A0A1G8Y7P9 1-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.