DPCstruct | MC26394

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)448 ± 81 aa
Standard deviation of domain lengths81.09
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score75.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)15.09
Pfam Score75.55
Assigned Pfam label(s) PF05699- PF12896- CL0448- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S7HTK4 2-436 NRNPLYPLYVKEFPKGLSIHRVADDARIATVVVRDMSQVAGYQWDKATGKFISVFYKDGTARVYDGFRSGRLVSLLRVGDGPVEAGV…
A0A1E3Q8N8 106-451 VSGDGDSRIFFNIFGHFSIEYIPLPSSLEKLTPISHASSADLSFHAFIAESQDHSLFILPLRVHFIRRFGNDLAHISSTSTKVQALL…
A0A087GFT4 27-562 None
A0A1W0A4I6 601-1034 None
A0A0G4MXV5 311-817 None
A0A165UAT2 17-627 None
R7UPI7 19-466 None
G4TCW5 69-473 None
A0A6S8X0Y2 68-517 None
A0A066VMD2 49-446 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.