DPCstruct | MC26369

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)110 ± 13 aa
Standard deviation of domain lengths13.44
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score90.15
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)54.17
Pfam Score100.00
Assigned Pfam label(s) PF00010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E3PRL3 308-397 EWHKMRRDSHKEVERRRRETINHGINELAKIVPNCEKNKGQILMRAADYIKMLKENEASNIEKWTMERLLLRNNIEQLAAQNEKLKE…
A0A642URM6 109-209 EWHRQRRENHKEVERRRRESINQGIKELAALIPTNDTNKAQILQRAVEYIKRLKENENNNIEKWTLEKLLTEQAMAELSASNDKLKS…
A0A1Y2GNJ3 1-119 None
A0A507F9H6 189-290 None
A0A197JT57 171-284 None
A0A0E9NJV1 548-659 None
I1BPD6 11-118 None
A0A0F4GI90 352-462 None
A0A1V1SRD2 206-324 None
A0A4V5NAG9 79-175 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.