DPCstruct | MC2635

Metacluster Properties and Pfam Annotations

Number of structural domains1943
Mean domain length (aa)156 ± 30 aa
Standard deviation of domain lengths30.32
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.07
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)11.20
Pfam Score53.02
Assigned Pfam label(s) PF20569- CL0020- CL0105- CL0458- PF09839

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6D0M0R2 3-125 SARPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRSRLPQQPGTAQEVQPAAWSALGIDAVVVGQVTPAPDGGYNVAYQLV…
A0A1V6HUF9 21-184 KGTSRYQAPQANLGAIRTAAVLPFVTLTGDAAHAEKVQRIFLGELLALGAVEVVESGRVAQLAVREQLVNTEALTPADFTRIGRELG…
A0A1G1ACH9 25-161 None
A0A3D0TJN8 13-183 None
A0A7C0U1U3 21-180 None
A0A1G2Y9A5 21-192 None
A0A1V5ZBR0 61-212 None
A0A423GNF9 58-191 None
A0A1R4GFZ7 6-168 None
A0A7W4BT93 28-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.