DPCstruct | MC26341

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)76 ± 3 aa
Standard deviation of domain lengths3.49
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score81.70
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)48.52
Pfam Score69.70
Assigned Pfam label(s) CL0123- PF19426

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3L8SR25 46-118 MEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIP
A0A2J8LDK2 92-168 MEEWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEADSKLKQVYIPTYTK
A0A164ZED2 363-442 None
A0A6I8PH54 217-285 None
A0A7M3RR53 461-539 None
A0A6V7WA97 198-271 None
B7PEJ8 212-291 None
A0A444SH00 123-195 None
A0A0S7JXC9 106-182 None
A0A7E6FAK5 328-407 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.