DPCstruct | MC26338

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)142 ± 17 aa
Standard deviation of domain lengths17.24
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score91.22
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)43.42
Pfam Score90.35
Assigned Pfam label(s) PF20659- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M3JE67 1-160 MTAPFLRAYALASIKACHARKISAMGGMAAQIPIKNDQIANRKALAFVKQDKEREATDGHDGTWVAHPDLVKVARDVFDTTMPQQNQ…
A0A2X3K8A5 3-120 AFIPSKDEERNNQVLNKVKADKALEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDVPITADQLLAPCDGERTEEGM…
A0A165A8D7 298-457 None
A0A7W0QPD9 332-507 None
W0RMA4 305-453 None
A0A656C3W0 57-203 None
A0A815PDP1 87-221 None
A0A135S7F8 304-447 None
A0A817D3B1 555-664 None
A0A2J7Z1U0 169-304 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.