DPCstruct | MC26280

Metacluster Properties and Pfam Annotations

Number of structural domains412
Mean domain length (aa)165 ± 32 aa
Standard deviation of domain lengths32.39
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.63
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)18.16
Pfam Score98.80
Assigned Pfam label(s) PF01161- PF07760

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A443HVH9 10-216 None
A0A7C6BZF5 259-417 None
A0A1S9B5R0 10-177 None
A0A3M7KZI1 712-864 None
A0A1W1X3A2 181-380 None
A0A662DE32 52-229 None
A0A1I8CKG3 98-335 None
A0A1I8CFZ8 19-176 None
A0A2N3GZI9 24-193 None
A0A7R8VDF5 337-493 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.