DPCstruct | MC26280

Metacluster Properties and Pfam Annotations

Number of structural domains412
Mean domain length (aa)165 ± 32 aa
Standard deviation of domain lengths32.39
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.63
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)18.16
Pfam Score98.80
Assigned Pfam label(s) PF01161- PF07760

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A133VDU7 3-152 LSSSAFENGKEIPSKYTCEGDDVSPPLSIEEVDPGTESLALVVDDPDAPGRVFDHWIIWNIPADADSIPEGVPPDEIVESLDGAIQG…
A0A482W1W3 15-166 PPLKISITYQSRNVEPGQELTPIEVKDEPAARWEANPAKYYTLVMFDPDAPSREDPKLADVKHWLVGNILGCEVSTGDVIAEYFGSG…
A0A5C8CAW7 13-166 None
A0A0D8XEK9 1-320 None
A0A7R8WY22 103-271 None
A0A1H1XZT0 299-459 None
A0A146H775 313-486 None
A0A7S2UZW4 33-182 None
A0A821U7L6 43-212 None
A0A1S1MLK8 371-534 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.