DPCstruct | MC26164

Metacluster Properties and Pfam Annotations

Number of structural domains433
Mean domain length (aa)150 ± 30 aa
Standard deviation of domain lengths30.04
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score89.77
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)19.51
Pfam Score99.23
Assigned Pfam label(s) PF00338- CL0159- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453RMQ2 50-241 KRNHGPIPKVDDISRYSVSISGLVNKHIQLSMDDIRMLPKYNVTATLQCAGNKRTAMSKVRKVRGVGWDVSALGNATWGGAKLSDVL…
A0A0G2EEH9 6-167 VDEEKWLLVIDGLVRHPFAITLPQLKSLPRTTLTAFHECYGSPLTPPDKALWRIGNVTWTGVKLSSLLDVAAPLARASFIWSEGLDR…
A0A6I4SVQ0 28-144 None
A0A3D1QX38 1-145 None
A0A0D2HRJ4 27-178 None
A0A7T5ET21 214-361 None
A0A2Z4I362 122-252 None
A0A847V6T5 89-285 None
A0A1V5BZ86 300-433 None
A0A7V9IJD5 170-303 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.