DPCstruct | MC26146

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)200 ± 27 aa
Standard deviation of domain lengths26.90
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score92.09
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.93
Pfam Score100.00
Assigned Pfam label(s) PF05985

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377A5G2 59-231 ENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCA…
A0A7C7RGI4 6-213 VGRGVDLALGYGDKVYEIEPELNKRIHDLYDDAKISLWAEFTPEFVKTIPNALEITTKSQDREEYVADPASGEELSEATVATLEKLR…
G2ZNG5 22-243 None
A0A6I3KZ05 13-258 None
A0A7W1L2I2 110-361 None
J3EQ02 38-262 None
A0A536SX48 296-516 None
A0A3M2UGR1 100-318 None
A0A149UHN8 10-207 None
H6SIR0 1-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.